Optimisation of Cinnamaldehyde-in-water Nanoemulsion Formulation using Central Composite Rotatable Design
نویسندگان
چکیده
منابع مشابه
Optimized preparation of celastrol-loaded polymeric nanomicelles using rotatable central composite design and response surface methodology.
Celastrol has been found to be a potent anti-inflammatory and antitumor plant derivative recently. Herein we established an accurate reverse phase HPLC (RP-HPLC) determination method of celastrol, and prepared an effective nanoscale drug delivery system from the optimized formulations of celastrol-loaded carboxyl functioned poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene ...
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Simvastatin is a poorly water-soluble drug, and bioavailability from its crystalline form is very low. The purpose of this investigation was to increase the solubility and dissolution rate of simvastatin by the preparation of nanosuspensions with Pluronic F127 and zirconium oxide (ZrO2) beads using a wet-milling technique at the laboratory scale. Prepared nanosuspensions were evaluated for part...
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ژورنال
عنوان ژورنال: Sains Malaysiana
سال: 2018
ISSN: 0126-6039
DOI: 10.17576/jsm-2018-4709-07